ZFIN is now using GRCz12tu for Genomic Data

Gene

cremb

ID

ZDB-GENE-050417-150

Name

cAMP responsive element modulator b

Symbol

cremb Nomenclature History

Previous Names

zgc:112054

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in retinal ganglion cell layer and spinal cord. Human ortholog(s) of this gene implicated in heart disease. Orthologous to human CREM (cAMP responsive element modulator).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:112054 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cremb Human Ortholog

No data available

Associated With cremb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004827	Basic-leucine zipper domain
Family	IPR001630	cAMP response element binding (CREB) protein
Homologous_superfamily	IPR046347	Basic-leucine zipper domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PU22	InterPro	355
UniProtKB:A0A8M9PLS1	InterPro	404
UniProtKB:A0A8M9PXG8	InterPro	394
UniProtKB:Q567H4	InterPro	108
UniProtKB:A0AB32TBC9	InterPro	259
UniProtKB:A0AC58IQF6	InterPro	230
UniProtKB:A0AC58IQF7	InterPro	230
UniProtKB:A0AC58IQG1	InterPro	167
UniProtKB:A0AC58IQG2	InterPro	220
UniProtKB:A0AC58IQG7	InterPro	269
UniProtKB:A0AC58IQH5	InterPro	145
UniProtKB:A0AC58IQH6	InterPro	155
UniProtKB:A0AC58IQH8	InterPro	118

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	cremb-204 (1) Ensembl	Ensembl	912 nt	Select Tool ZFIN BLAST
mRNA	cremb-201 (1) Ensembl	Ensembl	751 nt	Select Tool ZFIN BLAST
mRNA	cremb-202 (1) Ensembl	Ensembl	1,386 nt	Select Tool ZFIN BLAST
mRNA	cremb-203 (1) Ensembl	Ensembl	1,301 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations