Gene

wdr73

ID

ZDB-GENE-050417-126

Name

WD repeat domain 73

Symbol

wdr73 Nomenclature History

Previous Names

zgc:112071 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Involved in cerebellar Purkinje cell differentiation and midbrain development. Predicted to localize to cleavage furrow; cytosol; and spindle pole. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome. Orthologous to human WDR73 (WD repeat domain 73).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:112071 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Ben-Omran et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wdr73 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Galloway-Mowat syndrome 1	Alliance	Galloway-Mowat syndrome 1	251300

Associated With wdr73 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR042795	WD repeat-containing protein 73
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat