Gene

lifra

ID
ZDB-GENE-050327-16
Name
LIF receptor subunit alpha a
Symbol
lifra Nomenclature History
Previous Names
  • zgc:112989
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have cytokine binding activity; peptide hormone binding activity; and prolactin receptor activity. Predicted to be involved in prolactin signaling pathway. Predicted to localize to external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in osteochondrodysplasia. Orthologous to human LIFR (LIF receptor subunit alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lifra Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Stuve-Wiedemann syndrome/Schwartz-Jampel type 2 syndrome 601559
Associated With lifra Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003529 Long hematopoietin receptor, Gp130 family 2, conserved site
Domain IPR003961 Fibronectin type III
Domain IPR040817 Leukemia inhibitory factor receptor, D2 domain
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold Leukemia inhibitory factor receptor, D2 domain Long hematopoietin receptor, Gp130 family 2, conserved site
UniProtKB:A0A0R4IE17 930
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations