Gene

sorbs3

ID

ZDB-GENE-050327-1

Name

sorbin and SH3 domain containing 3

Symbol

sorbs3 Nomenclature History

Previous Names

si:dkey-162f21.1
zgc:113031

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to be involved in actin filament organization and cell adhesion. Is expressed in immature eye; integument; nervous system; pronephros; and spinal cord neural tube. Orthologous to human SORBS3 (sorbin and SH3 domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Malmquist et al., 2013

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Malmquist et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sorbs3 Human Ortholog

No data available

Associated With sorbs3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001452	SH3 domain
Domain	IPR003127	SoHo domain
Domain	IPR035607	Vinexin, SH3 domain 3
Domain	IPR035609	Vinexin, SH3 domain 1
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	SH3 domain	SH3-like domain superfamily	SoHo domain	Vinexin, SH3 domain 1	Vinexin, SH3 domain 3
UniProtKB:Q58ER3 InterPro	564
UniProtKB:A0A8M9Q3F5 InterPro	577
UniProtKB:A0A8M6Z825 InterPro	677
UniProtKB:F1R0C1 InterPro	617
UniProtKB:A0A8M2B9N0 InterPro	695

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sorbs3-201 (1) Ensembl	Havana	860 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sorbs3-203 (1) Ensembl	Havana	747 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sorbs3-204 (1) Ensembl	Havana	743 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sorbs3-205 (1) Ensembl	Havana	2534 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sorbs3-206 (1) Ensembl	Havana	756 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations