Gene

pex7

ID

ZDB-GENE-050320-105

Name

peroxisomal biogenesis factor 7

Symbol

pex7 Nomenclature History

Previous Names

zgc:103552

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have peroxisome matrix targeting signal-2 binding activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to localize to cytosol and peroxisomal matrix. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and rhizomelic chondrodysplasia punctata type 1. Orthologous to human PEX7 (peroxisomal biogenesis factor 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:103552 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pex7 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Peroxisome biogenesis disorder 9B	Alliance	Peroxisome biogenesis disorder 9B	614879
rhizomelic chondrodysplasia punctata type 1	Alliance	Rhizomelic chondrodysplasia punctata, type 1	215100

Associated With pex7 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Family	IPR044536	Peroxisomal targeting signal 2 receptor
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat