Gene
eps8l1a
- ID
- ZDB-GENE-050306-14
- Name
- EPS8 signaling adaptor L1a
- Symbol
- eps8l1a Nomenclature History
- Previous Names
-
- eps8l1
- zgc:113583
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to contribute to Rac guanyl-nucleotide exchange factor activity. Predicted to be involved in Rho protein signal transduction; positive regulation of ruffle assembly; and regulation of Rho protein signal transduction. Predicted to localize to ruffle membrane. Orthologous to human EPS8L1 (EPS8 like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR035462 | Eps8, SH3 domain |
| Domain | IPR041418 | SAM domain |
| Family | IPR039801 | Epidermal growth factor receptor kinase substrate 8-like |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Epidermal growth factor receptor kinase substrate 8-like | Eps8, SH3 domain | SAM domain | SH3 domain | SH3-like domain superfamily | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B857
|
522 | ||||||
|
UniProtKB:Q5CZQ5
|
522 | ||||||
|
UniProtKB:A0A8M3B0T2
|
509 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eps8l1a-201
(1)
|
Ensembl | 2,061 nt | ||
| mRNA |
eps8l1a-202
(1)
|
Ensembl | 843 nt | ||
| mRNA |
eps8l1a-203
(1)
|
Ensembl | 783 nt |
Interactions and Pathways
No data available
Plasmids
No data available