Gene

kat5b

ID

ZDB-GENE-030131-985

Name

K(lysine) acetyltransferase 5b

Symbol

kat5b Nomenclature History

Previous Names

htatip
im:6908768
wu:fb55b08
zgc:110752

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable histone H4K16 acetyltransferase activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to act upstream of or within DNA repair. Predicted to be located in chromatin and nuclear lumen. Predicted to be part of NuA4 histone acetyltransferase complex. Orthologous to human KAT5 (lysine acetyltransferase 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6908768 (1 image)
IMAGE:7140549 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kat5b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with dysmorphic facies, sleep disturbance, and brain abnormalities	619103

Associated With kat5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000953	Chromo/chromo shadow domain
Domain	IPR002717	Histone acetyltransferase domain, MYST-type
Domain	IPR025995	RNA binding activity-knot of a chromodomain
Domain	IPR040706	MYST, zinc finger domain
Family	IPR050603	MYST family histone acetyltransferases
Homologous_superfamily	IPR016181	Acyl-CoA N-acyltransferase
Homologous_superfamily	IPR016197	Chromo-like domain superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily