Gene

gpt

ID
ZDB-GENE-050302-11
Name
glutamic--pyruvic transaminase
Symbol
gpt Nomenclature History
Previous Names
  • gpt2
  • gpt2l
  • im:6791811
  • wu:fd46f01
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have L-alanine:2-oxoglutarate aminotransferase activity. Predicted to be involved in 2-oxoglutarate metabolic process and L-alanine metabolic process. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in liver. Orthologous to several human genes including GPT (glutamic--pyruvic transaminase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gpt Human Ortholog
No data available
Associated With gpt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004839 Aminotransferase, class I/classII
Family IPR045088 Aminotransferase ALAT1/2-like
Homologous_superfamily IPR015421 Pyridoxal phosphate-dependent transferase, major domain
Homologous_superfamily IPR015422 Pyridoxal phosphate-dependent transferase, small domain
Homologous_superfamily IPR015424 Pyridoxal phosphate-dependent transferase
Domain Details Per Protein
Protein Length Aminotransferase ALAT1/2-like Aminotransferase, class I/classII Pyridoxal phosphate-dependent transferase Pyridoxal phosphate-dependent transferase, major domain Pyridoxal phosphate-dependent transferase, small domain
UniProtKB:Q6NYL5 549
UniProtKB:A0A8M1NQS1 493
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations