vma22

ID

ZDB-GENE-050227-20

Name

vacuolar ATPase assembly factor VMA22

Symbol

vma22 Nomenclature History

Previous Names

ccdc115 (1)
zgc:113121

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable obsolete unfolded protein binding activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to be located in endoplasmic reticulum. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIo. Orthologous to human VMA22 (vacuolar ATPase assembly factor VMA22).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6905212 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With vma22 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
congenital disorder of glycosylation type IIo	Alliance	Congenital disorder of glycosylation, type IIo	616828

Associated With vma22 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR040357	Vma22/CCDC115

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:Q5EAR6	InterPro	206
UniProtKB:F1QSB2	InterPro	206
UniProtKB:A0AC58IJN9	InterPro	206
UniProtKB:A0AC58IJP1	InterPro	206
UniProtKB:A0AC58IJP9	InterPro	206
UniProtKB:A0AC58IJS9	InterPro	206
UniProtKB:A0AC58IJT1	InterPro	206