Gene

dlg1b

ID
ZDB-GENE-050222-3
Name
discs large MAGUK scaffold protein 1b
Symbol
dlg1b Nomenclature History
Previous Names
  • dlg1l
  • SAP-97B (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have phosphatase binding activity and protein kinase binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; endothelial cell proliferation; and establishment or maintenance of epithelial cell apical/basal polarity. Predicted to colocalize with ionotropic glutamate receptor complex. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Is expressed in retina; spinal cord; and tegmentum. Orthologous to human DLG1 (discs large MAGUK scaffold protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dlg1b Human Ortholog
No data available
Associated With dlg1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020590 Guanylate kinase, conserved site
Domain IPR001452 SH3 domain
Domain IPR001478 PDZ domain
Domain IPR004172 L27 domain
Domain IPR008144 Guanylate kinase-like domain
Domain IPR008145 Guanylate kinase/L-type calcium channel beta subunit
Domain IPR015143 L27-1
Domain IPR019583 Disks large homolog 1-4, PDZ-associated domain
Domain IPR019590 Disks large homologue 1, N-terminal PEST domain
Family IPR016313 Disks large 1-like
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Homologous_superfamily IPR036892 L27 domain superfamily
Domain Details Per Protein
Protein Length Disks large 1-like Disks large homolog 1-4, PDZ-associated domain Disks large homologue 1, N-terminal PEST domain Guanylate kinase, conserved site Guanylate kinase-like domain Guanylate kinase/L-type calcium channel beta subunit L27-1 L27 domain L27 domain superfamily PDZ domain PDZ superfamily P-loop containing nucleoside triphosphate hydrolase SH3 domain SH3-like domain superfamily
UniProtKB:Q5PYH5 827
UniProtKB:A0A8M3AVI6 955
UniProtKB:A0A8M9QIS4 763
UniProtKB:A0A8M3AN11 990
UniProtKB:A0A8M3ANR6 969
UniProtKB:A0A0R4IEK3 906
UniProtKB:A0A8M3AN35 950
UniProtKB:A0A8M2BB01 918
UniProtKB:A0A8M3B6A9 820
UniProtKB:A0A8M2BB75 894
UniProtKB:A0A8M2BAW9 927
UniProtKB:A0A8M2BAT2 873
UniProtKB:A0A8M3B688 966
UniProtKB:A0A8M2BAT6 957
UniProtKB:A0A8M3AYM3 911
UniProtKB:A0A8M9Q8G6 871
UniProtKB:A0A8M9QMI5 989
UniProtKB:A0A8M2BB05 736
UniProtKB:A0A8M2BB74 951
UniProtKB:A0A8M2BAX2 841
UniProtKB:A0A8M2BAS7 950
UniProtKB:A0A8M3ANU0 836
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations