Gene

unc13a

ID
ZDB-GENE-140722-1
Name
unc-13 homolog A (C. elegans)
Symbol
unc13a Nomenclature History
Previous Names
  • si:dkey-110c1.7
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity; diacylglycerol binding activity; and phospholipid binding activity. Predicted to be involved in chemical synaptic transmission; intracellular signal transduction; and synaptic vesicle maturation.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Sánchez et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With unc13a Human Ortholog
No data available
Associated With unc13a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000008 C2 domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR010439 MUN domain
Domain IPR014770 Munc13 homology 1
Domain IPR014772 Mammalian uncoordinated homology 13, domain 2
Domain IPR037302 Protein Unc-13, C2B domain
Family IPR027080 Protein Unc-13
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR046349 C1-like domain superfamily
Domain Details Per Protein
Protein Length C1-like domain superfamily C2 domain C2 domain superfamily Mammalian uncoordinated homology 13, domain 2 Munc13 homology 1 MUN domain Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein Unc-13 Protein Unc-13, C2B domain
UniProtKB:A0A8M3AXQ9 1784
UniProtKB:A0A8M3AUR4 1763
UniProtKB:A0A8M3AUQ9 1806
UniProtKB:Q1LXS6 1742
UniProtKB:A0A8M3AN14 1818
UniProtKB:A0A8M3B5J4 1797
UniProtKB:A0A8M3AMA8 1799
UniProtKB:A0A8M3AXQ5 1816
UniProtKB:A0A8M3AN19 1787
UniProtKB:A0A8M9PRV9 1223
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:dkey-110c1.7-202 (1) Ensembl 1,584 nt
mRNA si:dkey-110c1.7-203 (1) Ensembl 3,832 nt
mRNA unc13a-201 (1) Ensembl 5,229 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations