Gene

cers1

ID
ZDB-GENE-050208-406
Name
ceramide synthase 1
Symbol
cers1 Nomenclature History
Previous Names
  • si:dkey-49m19.7
  • wu:fb75h07
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to localize to endoplasmic reticulum. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 8. Is expressed in several structures, including intermediate cell mass of mesoderm; intestine; nervous system; otic vesicle; and trigeminal neural crest. Orthologous to human CERS1 (ceramide synthase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Brondolin et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cers1 Human Ortholog
No data available
Associated With cers1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006634 TRAM/LAG1/CLN8 homology domain
Family IPR016439 Sphingosine N-acyltransferase Lag1/Lac1-like
Domain Details Per Protein
Protein Length Sphingosine N-acyltransferase Lag1/Lac1-like TRAM/LAG1/CLN8 homology domain
UniProtKB:F1Q5B1 358
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations