Gene
ift80
- ID
- ZDB-GENE-041212-50
- Name
- intraflagellar transport 80 homolog (Chlamydomonas)
- Symbol
- ift80 Nomenclature History
- Previous Names
-
- wu:fj11a06
- zgc:101763
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Involved in several processes, including cilium assembly; convergent extension; and retina morphogenesis in camera-type eye. Predicted to localize to centrosome; cilium; and intraciliary transport particle B. Used to study asphyxiating thoracic dystrophy; asphyxiating thoracic dystrophy 2; and ciliopathy. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 2. Is expressed in several structures, including eye; notochord; pectoral fin; pectoral fin bud; and pronephric duct. Orthologous to human IFT80 (intraflagellar transport 80).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101763 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| asphyxiating thoracic dystrophy 2 | Alliance | Short-rib thoracic dysplasia 2 with or without polydactyly | 611263 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M2BKN3
|
779 | |||
|
UniProtKB:Q5PRA9
|
777 |
Interactions and Pathways
No data available
Plasmids
No data available