ZFIN is now using GRCz12tu for Genomic Data

Gene

mical3b

ID

ZDB-GENE-050211-1

Name

microtubule associated monooxygenase, calponin and LIM domain containing 3b

Symbol

mical3b Nomenclature History

Previous Names

si:dkey-153k10.11
si:dkeyp-27e10.1

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable F-actin monooxygenase activity; FAD binding activity; and actin binding activity. Predicted to be involved in actin filament depolymerization. Predicted to be located in nucleus. Is expressed in floor plate; hindbrain nucleus; octaval nerve motor nucleus; octaval nerve sensory nucleus; and spinal cord. Orthologous to human MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Xue et al., 2010

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mical3b Human Ortholog

No data available

Associated With mical3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001715	Calponin homology domain
Domain	IPR001781	Zinc finger, LIM-type
Domain	IPR002938	FAD-binding domain
Domain	IPR022735	bMERB domain
Domain	IPR057494	[F-actin]-monooxygenase MICAL1-3-like, Rossman domain
Family	IPR050540	F-actin Monooxygenase Mical
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily
Homologous_superfamily	IPR036872	CH domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:F1QWK4	InterPro
UniProtKB:A0A8M9PRL9	InterPro	1572
UniProtKB:A0A8M9PRL3	InterPro	1734
UniProtKB:A0A8M9PV05	InterPro	1572
UniProtKB:A0A8M9PHR6	InterPro	1698
UniProtKB:A0A8M9Q8P9	InterPro	1699
UniProtKB:A0A8M9PY14	InterPro	1540
UniProtKB:A0A8M9PXR3	InterPro	1709
UniProtKB:A0A8M9Q0Z6	InterPro	1735
UniProtKB:A0A8M9Q100	InterPro	1033
UniProtKB:A0A8M9PES7	InterPro	1735
UniProtKB:A0A8M9PET2	InterPro	1682
UniProtKB:A0A8M3ARC5	InterPro	1682
UniProtKB:A0A8M9Q689	InterPro	1709
UniProtKB:A0A8M9QBR6	InterPro	1734
UniProtKB:A0A8M3AYP9	InterPro	1699
UniProtKB:A0A8M9Q4D5	InterPro	1698
UniProtKB:A0AB13A8G0	InterPro	1662
UniProtKB:A0AB32TSJ2	InterPro	1713
UniProtKB:A0AC58J7T3	InterPro	1786
UniProtKB:A0AC58J7T8	InterPro	1760
UniProtKB:A0AC58J7T9	InterPro	1785
UniProtKB:A0AC58J7U0	InterPro	1785
UniProtKB:A0AC58J7U2	InterPro	1723
UniProtKB:A0AC58J7U3	InterPro	1709
UniProtKB:A0AC58J7U5	InterPro	1759
UniProtKB:A0AC58J7U7	InterPro	1698
UniProtKB:A0AC58J7U8	InterPro	1698
UniProtKB:A0AC58J7U9	InterPro	1697
UniProtKB:A0AC58J7V0	InterPro	1759
UniProtKB:A0AC58J7V3	InterPro	1697
UniProtKB:A0AC58J7V4	InterPro	1686
UniProtKB:A0AC58J7V5	InterPro	1687
UniProtKB:A0AC58J7V6	InterPro	1682
UniProtKB:A0AC58J7V7	InterPro	1676
UniProtKB:A0AC58J7V8	InterPro	1698
UniProtKB:A0AC58J7V9	InterPro	1713
UniProtKB:A0AC58J7W0	InterPro	1671
UniProtKB:A0AC58J7W1	InterPro	1671
UniProtKB:A0AC58J7W2	InterPro	1699
UniProtKB:A0AC58J7W3	InterPro	1672
UniProtKB:A0AC58J7W4	InterPro	1672
UniProtKB:A0AC58J7W5	InterPro	1676
UniProtKB:A0AC58J7W6	InterPro	1675
UniProtKB:A0AC58J7W7	InterPro	1662
UniProtKB:A0AC58J7W8	InterPro	1723
UniProtKB:A0AC58J7W9	InterPro	1656
UniProtKB:A0AC58J7X0	InterPro	1650
UniProtKB:A0AC58J7X1	InterPro	1656
UniProtKB:A0AC58J7X2	InterPro	1655
UniProtKB:A0AC58J7X4	InterPro	1672
UniProtKB:A0AC58J7X5	InterPro	1650
UniProtKB:A0AC58J7X8	InterPro	1673
UniProtKB:A0AC58J7X9	InterPro	1672
UniProtKB:A0AC58J7Y1	InterPro	1675
UniProtKB:A0AC58J7Y2	InterPro	1618
UniProtKB:A0AC58J7Y3	InterPro	1649
UniProtKB:A0AC58J7Y7	InterPro	1635
UniProtKB:A0AC58J7Y9	InterPro	1535
UniProtKB:A0AC58J7Z9	InterPro	1510
UniProtKB:A0AC58J803	InterPro	1635

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mical3b-201 (1) Ensembl	Ensembl	5,964 nt	Select Tool ZFIN BLAST
mRNA	mical3b-202 (1) Ensembl	Ensembl	493 nt	Select Tool ZFIN BLAST
mRNA	mical3b-203 (1) Ensembl	Ensembl	5,885 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations