Gene
kics2
- ID
- ZDB-GENE-041210-104
- Name
- KICSTOR subunit 2
- Symbol
- kics2 Nomenclature History
- Previous Names
-
- si:ch211-125a15.1
- zgc:136251
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to be involved in several processes, including cellular response to amino acid starvation; cellular response to glucose starvation; and negative regulation of TORC1 signaling. Predicted to be located in lysosomal membrane. Predicted to be part of KICSTOR complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 83. Orthologous to human KICS2 (KICSTOR subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Buchert et al., 2025
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Buchert et al., 2025
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 83 | Alliance | Intellectual developmental disorder, autosomal recessive 83 | 621100 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | KICSTOR complex protein C12orf66-like, central domain superfamily | KICSTOR subunit 2 |
|---|---|---|---|---|
| UniProtKB:B7ZUU9 | InterPro | 449 | ||
| UniProtKB:Q1L8F9 | InterPro | 449 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-125a15.1-201
(1)
|
Ensembl | 1,726 nt |
Interactions and Pathways
No data available
Plasmids
No data available