Gene

pygl

ID

ZDB-GENE-041205-1

Name

phosphorylase, glycogen, liver

Symbol

pygl Nomenclature History

Previous Names

zgc:66314

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have glycogen phosphorylase activity and pyridoxal phosphate binding activity. Predicted to be involved in glycogen catabolic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease VI; and lactic acidosis. Is expressed in eye; heart; kidney; liver; and muscle. Orthologous to human PYGL (glycogen phosphorylase L).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pygl Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
glycogen storage disease VI	Alliance	Glycogen storage disease VI	232700

Associated With pygl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR035090	Phosphorylase pyridoxal-phosphate attachment site
Family	IPR000811	Glycosyl transferase, family 35
Family	IPR011833	Glycogen/starch/alpha-glucan phosphorylase