Gene
pcdh2ab9
- ID
- ZDB-GENE-041118-8
- Name
- protocadherin 2 alpha b 9
- Symbol
- pcdh2ab9 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human PCDHAC2 (protocadherin alpha subfamily C, 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Tada et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-pcdh2a | N/A | Emond et al., 2008 |
| MO2-pcdh2a | N/A | Emond et al., 2008 |
1 - 2 of 2
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin conserved site | Cadherin, C-terminal catenin-binding domain | Cadherin, cytoplasmic C-terminal domain | Cadherin-like | Cadherin-like superfamily | Cadherin, N-terminal | Protocadherin/Cadherin-related Cell Adhesion |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q60I68
|
940 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pcdh2ab9-201
(1)
|
Ensembl | 7,397 nt | ||
| mRNA |
pcdh2ab9-207
(1)
|
Ensembl | 7,916 nt | ||
| mRNA |
pcdh2ab9-208
(1)
|
Ensembl | 8,101 nt | ||
| mRNA |
pcdh2ab9-209
(1)
|
Ensembl | 7,718 nt | ||
| mRNA |
pcdh2ab9-210
(1)
|
Ensembl | 7,715 nt |
1 - 5 of 6 Show all
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-262J3 | ZFIN Curated Data | |
| Contained in | BAC | DKEYP-115D7 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:194884 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:194891 | ZFIN Curated Data |
1 - 4 of 4
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001009596 (1) | 3436 nt | ||
| Genomic | GenBank:CR847851 (1) | 161657 nt | ||
| Polypeptide | UniProtKB:Q60I68 (1) | 940 aa |
No data available
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Tan, Y.P., Li, S., Jiang, X.J., Loh, W., Foo, Y.K., Loh, C.B., Xu, Q., Yuen, W.H., Jones, M., Fu, J., Venkatesh, B., and Yu, W.P. (2010) Regulation of protocadherin gene expression by multiple neuron-restrictive silencer elements scattered in the gene cluster. Nucleic acids research. 38(15):4985-4997
- Emond, M.R., and Jontes, J.D. (2008) Inhibition of protocadherin-alpha function results in neuronal death in the developing zebrafish. Developmental Biology. 321(1):175-187
- Tada, M.N., Senzaki, K., Tai, Y., Morishita, H., Tanaka, Y.Z., Murata, Y., Ishii, Y., Asakawa, S., Shimizu, N., Sugino, H., and Yagi, T. (2004) Genomic organization and transcripts of the zebrafish Protocadherin genes. Gene. 340(2):197-211
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 5 of 5
Show