Gene

plekha8

ID
ZDB-GENE-041114-69
Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Symbol
plekha8 Nomenclature History
Previous Names
  • fc68b04
  • wu:fc68b04
  • zgc:101886
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in ER to Golgi ceramide transport and intermembrane lipid transfer. Predicted to localize to cytosol and membrane. Orthologous to several human genes including PLEKHA8 (pleckstrin homology domain containing A8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plekha8 Human Ortholog
No data available
Associated With plekha8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR014830 Glycolipid transfer protein domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036497 Glycolipid transfer protein superfamily
Domain Details Per Protein
Protein Length Glycolipid transfer protein domain Glycolipid transfer protein superfamily PH-like domain superfamily Pleckstrin homology domain
UniProtKB:Q5U3N0 549
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations