Gene
ino80
- ID
- ZDB-GENE-041014-72
- Name
- INO80 complex ATPase subunit
- Symbol
- ino80 Nomenclature History
- Previous Names
-
- si:ch211-244p18.3
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable ATP hydrolysis activity and histone binding activity. Predicted to be involved in DNA repair and chromatin remodeling. Predicted to be located in chromosome; nucleus; and spindle. Predicted to be part of Ino80 complex. Is expressed in hematopoietic multipotent progenitor cell. Orthologous to human INO80 (INO80 complex ATPase subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ding et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Shin et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000330 | SNF2, N-terminal |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR020838 | DBINO domain |
| Domain | IPR031047 | DNA helicase INO80, DEAQ-box helicase domain |
| Domain | IPR049730 | SNF2/RAD5-like, C-terminal helicase domain |
| Family | IPR050520 | INO80/SWR1 chromatin remodeling helicase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR038718 | SNF2-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DBINO domain | DNA helicase INO80, DEAQ-box helicase domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | INO80/SWR1 chromatin remodeling helicase | P-loop containing nucleoside triphosphate hydrolase | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | SNF2/RAD5-like, C-terminal helicase domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3ARX1 | InterPro | 1558 | |||||||||
| UniProtKB:Q5SPB7 | InterPro | 1552 | |||||||||
| UniProtKB:A0A8M3B1Z5 | InterPro | 1557 | |||||||||
| UniProtKB:A0A8M3AZ14 | InterPro | 1556 | |||||||||
| UniProtKB:A0AB32TCG5 | InterPro | 1551 |
Interactions and Pathways
No data available
Plasmids
No data available