Gene
ak9
- ID
- ZDB-GENE-041014-337
- Name
- adenylate kinase 9
- Symbol
- ak9 Nomenclature History
- Previous Names
-
- akd1
- si:ch211-199m3.2
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable (d)CMP kinase activity and UMP kinase activity. Acts upstream of or within cilium movement. Located in cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 89. Orthologous to human AK9 (adenylate kinase 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Choksi et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Choksi et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa43482 | Allele with one point mutation | Unknown | Splice Site | ENU |
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Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spermatogenic failure 89 | Alliance | Spermatogenic failure 89 | 620705 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adenylate kinase/UMP-CMP kinase | Cilia- and flagella-associated protein 206 | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|
|
UniProtKB:A0A8M3ALP1
|
1697 | |||
|
UniProtKB:A0A2R9YJL3
|
1762 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-199M3 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_009294789 (1) | |||
| Genomic | GenBank:BX571790 (1) | 200944 nt | ||
| Polypeptide | UniProtKB:A0A2R9YJL3 (1) | 1762 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Choksi, S.P., Babu, D., Lau, D., Yu, X., Roy, S. (2014) Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Development (Cambridge, England). 141:3410-9
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