Gene
rad51c
- ID
- ZDB-GENE-041010-204
- Name
- RAD51 paralog C
- Symbol
- rad51c Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to contribute to crossover junction endodeoxyribonuclease activity and four-way junction DNA binding activity. Predicted to be involved in DNA repair and reciprocal meiotic recombination. Predicted to colocalize with Holliday junction resolvase complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group O and hereditary breast ovarian cancer syndrome. Orthologous to human RAD51C (RAD51 paralog C).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101596 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ramanagoudr-Bhojappa et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Fanconi anemia complementation group O | Alliance | Fanconi anemia, complementation group O | 613390 |
{Breast-ovarian cancer, familial, susceptibility to, 3} | 613399 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR013632 | DNA recombination and repair protein Rad51-like, C-terminal |
Domain | IPR020588 | DNA recombination and repair protein RecA-like, ATP-binding domain |
Family | IPR016467 | DNA recombination and repair protein, RecA-like |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
Protein | Length | DNA recombination and repair protein Rad51-like, C-terminal | DNA recombination and repair protein, RecA-like | DNA recombination and repair protein RecA-like, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|
UniProtKB:A0A8M9QC24
|
362 | ||||
UniProtKB:A0A8M9QKP1
|
337 | ||||
UniProtKB:Q5XJT2
|
362 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
rad51c-202
(1)
|
1638 nt |
Interactions and Pathways
No data available
Plasmids
No data available