Gene

gtpbp1l

ID

ZDB-GENE-041007-2

Name

GTP binding protein 1, like

Symbol

gtpbp1l Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have translation elongation factor activity. Predicted to be involved in translational elongation. Is expressed in several structures, including alar plate midbrain region; hatching gland; lens; polster; and solid lens vesicle. Orthologous to human GTPBP1 (GTP binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110390 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Lo et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gtpbp1l Human Ortholog

No data available

Associated With gtpbp1l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000795	Translational (tr)-type GTP-binding domain
Domain	IPR004161	Translation elongation factor EFTu-like, domain 2
Domain	IPR035531	GTP binding protein 1-like, GTP-binding domain
Family	IPR050055	Elongation factor Tu GTPase
Homologous_superfamily	IPR009000	Translation protein, beta-barrel domain superfamily
Homologous_superfamily	IPR009001	Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase