Gene

rtknb

ID
ZDB-GENE-040912-64
Name
rhotekin b
Symbol
rtknb Nomenclature History
Previous Names
  • rtkn2b
  • si:dkey-264m23.3
  • zgc:101635
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have GTP-Rho binding activity. Predicted to be involved in actomyosin contractile ring assembly; protein localization to mitotic actomyosin contractile ring; and septin ring organization. Predicted to localize to actomyosin contractile ring. Is expressed in several structures, including head mesenchyme; lens; otic vesicle; pectoral fin bud; and solid lens vesicle. Orthologous to several human genes including RTKN (rhotekin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rtknb Human Ortholog
No data available
Associated With rtknb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR011072 HR1 rho-binding domain
Domain IPR012966 Anillin homology domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036274 HR1 repeat superfamily
Domain Details Per Protein
Protein Length Anillin homology domain HR1 repeat superfamily HR1 rho-binding domain PH-like domain superfamily Pleckstrin homology domain
UniProtKB:E7F528 499
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA rtkn2b-201 (1) Havana 1040 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations