pnp5b

ID

ZDB-GENE-040912-54

Name

purine nucleoside phosphorylase 5b

Symbol

pnp5b Nomenclature History

Previous Names

zgc:101740 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable purine-nucleoside phosphorylase activity. Predicted to be involved in purine ribonucleoside salvage. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in purine nucleoside phosphorylase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human PNP (purine nucleoside phosphorylase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101740 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pnp5b Human Ortholog

No data available

Associated With pnp5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018099	Purine phosphorylase, family 2, conserved site
Domain	IPR000845	Nucleoside phosphorylase domain
Family	IPR011268	Purine nucleoside phosphorylase
Family	IPR011270	Purine nucleoside phosphorylase I, inosine/guanosine-specific
Homologous_superfamily	IPR035994	Nucleoside phosphorylase superfamily