ZFIN is now using GRCz12tu for Genomic Data
Gene
malb
- ID
- ZDB-GENE-050417-175
- Name
- mal, T cell differentiation protein (MAL blood group) b
- Symbol
- malb Nomenclature History
- Previous Names
-
- mal
- im:7142606
- zgc:101772
- zgc:112003
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination and protein insertion into plasma membrane. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Is expressed in several structures, including cranial ganglion; hatching gland; mucus secreting cell; olfactory system; and pronephric duct. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy and metachromatic leukodystrophy. Orthologous to human MAL (mal, T cell differentiation protein (MAL blood group)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7142606 (1 image)
- MGC:101772 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Leukodystrophy, hypomyelinating, 28 | 620978 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Marvel domain | MARVEL domain-containing and chemokine-like factor proteins | Myelin and lymphocyte (MAL) protein |
|---|---|---|---|---|---|
| UniProtKB:Q66ID0 | InterPro | 159 | |||
| UniProtKB:Q567J3 | InterPro | 152 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers