Gene
cldn2
- ID
- ZDB-GENE-040912-26
- Name
- claudin 2
- Symbol
- cldn2 Nomenclature History
- Previous Names
-
- zgc:92260
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have structural molecule activity. Predicted to localize to bicellular tight junction; integral component of membrane; and plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 29. Is expressed in brain; eye; gonad; kidney; and liver. Orthologous to several human genes including CLDN2 (claudin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92260 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Azoospermia, obstructive, with nephrolithiasis | 301060 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Claudin | Claudin, conserved site | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|---|
|
UniProtKB:A0A8M2BHN3
|
270 |
Interactions and Pathways
No data available
Plasmids
No data available