Gene
agbl5
- ID
- ZDB-GENE-040822-29
- Name
- AGBL carboxypeptidase 5
- Symbol
- agbl5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have metallocarboxypeptidase activity and tubulin binding activity. Involved in chordate embryonic development and cilium assembly. Predicted to localize to several cellular components, including cytosol; midbody; and mitotic spindle. Human ortholog(s) of this gene implicated in retinitis pigmentosa 75. Is expressed in several structures, including Kupffer's vesicle; axis; forerunner cell group; nervous system; and pronephros. Orthologous to human AGBL5 (ATP/GTP binding protein like 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:91997 (20 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 75 | Alliance | Retinitis pigmentosa 75 | 617023 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytosolic carboxypeptidase-like protein 5 catalytic domain | Cytosolic carboxypeptidase, N-terminal | Peptidase M14, carboxypeptidase A |
|---|---|---|---|---|
|
UniProtKB:A0A8M6Z5B1
|
886 | |||
|
UniProtKB:Q68EI3
|
885 |
Interactions and Pathways
No data available
Plasmids
No data available