Gene
lamtor2
- ID
- ZDB-GENE-040801-63
- Name
- late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
- Symbol
- lamtor2 Nomenclature History
- Previous Names
-
- zgc:100811 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in several processes, including cellular response to amino acid stimulus; positive regulation of TORC1 signaling; and regulation of cell growth. Predicted to be located in late endosome. Predicted to be part of Ragulator complex. Predicted to be active in lysosomal membrane. Orthologous to human LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Immunodeficiency due to defect in MAPBP-interacting protein | 610798 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ragulator complex protein LAMTOR2-like | Roadblock/LAMTOR2 domain |
|---|---|---|---|
|
UniProtKB:F1R3H0
|
125 | ||
|
UniProtKB:Q6DEG4
|
125 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lamtor2-201
(1)
|
Ensembl | 785 nt |
Interactions and Pathways
No data available
Plasmids
No data available