Gene
crhbp
- ID
- ZDB-GENE-040801-196
- Name
- corticotropin releasing hormone binding protein
- Symbol
- crhbp Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable corticotropin-releasing hormone binding activity. Predicted to be involved in hormone-mediated signaling pathway; negative regulation of corticotropin secretion; and negative regulation of corticotropin-releasing hormone receptor activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain; heart; neurons; and retina. Human ortholog(s) of this gene implicated in depressive disorder. Orthologous to human CRHBP (corticotropin releasing hormone binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907482 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR056177 | Corticotropin-releasing factor binding protein, N-terminal domain |
| Domain | IPR056178 | Corticotropin-releasing factor binding protein, C-terminal domain |
| Family | IPR008435 | Corticotropin-releasing factor-binding protein |
| Homologous_superfamily | IPR035914 | Spermadhesin, CUB domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Corticotropin-releasing factor-binding protein | Corticotropin-releasing factor binding protein, C-terminal domain | Corticotropin-releasing factor binding protein, N-terminal domain | Spermadhesin, CUB domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q6DG79 | InterPro | 321 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available