Gene

ptpa

ID

ZDB-GENE-040801-11

Name

protein phosphatase 2 phosphatase activator

Symbol

ptpa Nomenclature History

Previous Names

fc23d07
ppp2r4 (1)
wu:fc23d07
zgc:92766

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have peptidyl-prolyl cis-trans isomerase activity and protein tyrosine phosphatase activator activity. Predicted to be involved in mitotic spindle organization. Predicted to localize to cytoplasm; nucleus; and protein phosphatase type 2A complex. Orthologous to human PTPA (protein phosphatase 2 phosphatase activator).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6908074 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptpa Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Parkinson's disease 25	Alliance	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	620482

Associated With ptpa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR004327	Phosphotyrosyl phosphatase activator, PTPA
Homologous_superfamily	IPR037218	PTPA superfamily
Homologous_superfamily	IPR043170	Phosphotyrosyl phosphatase activator, C-terminal lid domain