Gene

b4galt7

ID

ZDB-GENE-040727-3

Name

xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)

Symbol

b4galt7 Nomenclature History

Previous Names

zgc:110571

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable xylosylprotein 4-beta-galactosyltransferase activity. Acts upstream of or within several processes, including hatching behavior; proteoglycan biosynthetic process; and thigmotaxis. Predicted to be located in Golgi cisterna membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and Ehlers-Danlos syndrome spondylodysplastic type 1. Orthologous to human B4GALT7 (beta-1,4-galactosyltransferase 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Delbaere et al., 2019

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 10 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With b4galt7 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Ehlers-Danlos syndrome spondylodysplastic type 1	Alliance	Ehlers-Danlos syndrome, spondylodysplastic type, 1	130070

Associated With b4galt7 Via Experimental Models

Human Disease	Fish	Conditions	Citations
Ehlers-Danlos syndrome	b4galt7^{hi1516Tg/hi1516Tg}	standard conditions	Nissen et al., 2006
Ehlers-Danlos syndrome	b4galt7^{hi4063aTg/hi4063aTg}	standard conditions	Nissen et al., 2006

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR027791	Galactosyltransferase, C-terminal
Domain	IPR027995	Galactosyltransferase, N-terminal
Family	IPR003859	Beta-1,4-galactosyltransferase
Homologous_superfamily	IPR029044	Nucleotide-diphospho-sugar transferases