Gene

oxct1a

ID

ZDB-GENE-040723-3

Name

3-oxoacid CoA transferase 1a

Symbol

oxct1a Nomenclature History

Previous Names

oxct1
scot (1)
SAGm18B (2)
wu:fj36f06
wu:fj48g08
zgc:92003

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have 3-oxoacid CoA-transferase activity. Predicted to be involved in ketone body catabolic process. Predicted to localize to mitochondrion. Is expressed in somite. Orthologous to human OXCT1 (3-oxoacid CoA-transferase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from Rauch et al., 2003

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With oxct1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Succinyl CoA:3-oxoacid CoA transferase deficiency	245050

Associated With oxct1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR004164	Coenzyme A transferase active site
Binding_site	IPR004163	Coenzyme A transferase binding site
Domain	IPR012791	3-oxoacid CoA-transferase, subunit B
Domain	IPR012792	3-oxoacid CoA-transferase, subunit A
Family	IPR004165	Coenzyme A transferase family I
Family	IPR014388	3-oxoacid CoA-transferase
Homologous_superfamily	IPR037171	NagB/RpiA transferase-like

Domain Details Per Protein

Protein	Length	3-oxoacid CoA-transferase	3-oxoacid CoA-transferase, subunit A	3-oxoacid CoA-transferase, subunit B	Coenzyme A transferase active site	Coenzyme A transferase binding site	Coenzyme A transferase family I	NagB/RpiA transferase-like
UniProtKB:Q6AZB2 InterPro	525

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	oxct1a-201 (1) Ensembl	Havana	2666 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	oxct1a-203 (1) Ensembl	Havana	830 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	oxct1a-204 (1) Ensembl	Havana	719 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	oxct1a-002 (1) Ensembl	Havana	492 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations