ZFIN is now using GRCz12tu for Genomic Data
Gene
nudt2
- ID
- ZDB-GENE-040718-7
- Name
- nudix (nucleoside diphosphate linked moiety X)-type motif 2
- Symbol
- nudt2 Nomenclature History
- Previous Names
-
- zgc:91915
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. Predicted to be involved in AMP biosynthetic process and ATP biosynthetic process. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human NUDT2 (nudix hydrolase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:91915 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with or without peripheral neuropathy | 619844 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020084 | NUDIX hydrolase, conserved site |
| Domain | IPR000086 | NUDIX hydrolase domain |
| Family | IPR003565 | Bis(5'-nucleosyl)-tetraphosphatase |
| Family | IPR051325 | Nudix hydrolase domain-containing protein |
| Homologous_superfamily | IPR015797 | NUDIX hydrolase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Bis(5'-nucleosyl)-tetraphosphatase | NUDIX hydrolase, conserved site | NUDIX hydrolase domain | Nudix hydrolase domain-containing protein | NUDIX hydrolase-like domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6DG97 | InterPro | 147 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers