Gene

kdm8

ID

ZDB-GENE-040718-411

Name

lysine (K)-specific demethylase 8

Symbol

kdm8 Nomenclature History

Previous Names

jmjd5 (1)
zgc:173863
zgc:91962

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have chromatin binding activity and histone demethylase activity (H3-K36 specific). Predicted to be involved in G2/M transition of mitotic cell cycle; histone H3-K36 demethylation; and regulation of gene expression. Predicted to localize to nucleus. Orthologous to human KDM8 (lysine demethylase 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kdm8 Human Ortholog

No data available

Associated With kdm8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003347	JmjC domain
Domain	IPR041667	Cupin-like domain 8

Domain Details Per Protein

Protein	Length	Cupin-like domain 8	JmjC domain
UniProtKB:A0A8M3B173 InterPro	224
UniProtKB:A0A2R8QBH1 InterPro	259
UniProtKB:A8E534 InterPro	406
UniProtKB:A0A0R4IGD4 InterPro	406

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	kdm8-203 (1) Ensembl	Havana	1690 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	kdm8-202 (1) Ensembl	Havana	1396 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations