Gene

rbm24a

ID
ZDB-GENE-040628-1
Name
RNA binding motif protein 24a
Symbol
rbm24a Nomenclature History
Previous Names
  • rbm24
  • seb-4 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Enables RNA binding activity. Involved in negative regulation of nuclear-transcribed mRNA poly(A) tail shortening and positive regulation of sarcomere organization. Acts upstream of or within several processes, including embryonic organ morphogenesis; epithelial cell differentiation; and striated muscle tissue development. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including cardiovascular system; cephalic musculature; immature eye; segmental plate; and sensory system. Used to study cataract and microphthalmia. Orthologous to human RBM24 (RNA binding motif protein 24).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
30 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sdu28Allele with one deletionExon 1Frameshift, Premature StopTALEN
1 - 1 of 1
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Sequence Targeting Reagents
1 - 10 of 12
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Human Disease
Associated With rbm24a Human Ortholog
No data available
Associated With rbm24a Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Family IPR050886 RNA-binding_regulatory_proteins
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
1 - 4 of 4
Domain Details Per Protein
Protein Length Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA-binding_regulatory_proteins RNA recognition motif domain
UniProtKB:B3DI77 230
UniProtKB:Q76LC6 230
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 19
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rbm24a-201 (1) Ensembl 664 nt
mRNA rbm24a-202 (1) Ensembl 3,029 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(cryaa:rbm24a_delRRM-GFP)
  • Danio rerio
1Shao et al., 2020
Tg(myl7:rbm24a-2A-GFP)
  • Danio rerio
1Shao et al., 2020
1 - 2 of 2
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-108K24
Contained inFosmidCH1073-175O15ZFIN Curated Data
EncodescDNAMGC:194503ZFIN Curated Data
EncodescDNAMGC:194514ZFIN Curated Data
1 - 4 of 4
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRBM246
Conserved genome location (synteny) (1)
Amino acid sequence comparison (4)
MouseRbm2413
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
Citations
1 - 10 of 13
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