Gene
nudt15
- ID
- ZDB-GENE-040625-95
- Name
- nudix (nucleoside diphosphate linked moiety X)-type motif 15
- Symbol
- nudt15 Nomenclature History
- Previous Names
-
- zgc:86852
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity. Predicted to be involved in dGTP catabolic process. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in poor metabolism of thiopurines 2. Orthologous to human NUDT15 (nudix hydrolase 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6902873 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| poor metabolism of thiopurines 2 | Alliance | {Thiopurines, poor metabolism of, 2} | 616903 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NUDIX hydrolase | NUDIX hydrolase, conserved site | NUDIX hydrolase domain | NUDIX hydrolase-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A2R8RL21
|
172 | ||||
|
UniProtKB:A0A8M1N029
|
155 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nudt15-201
(1)
|
Ensembl | 1,009 nt | ||
| mRNA |
nudt15-202
(1)
|
Ensembl | 894 nt |
Interactions and Pathways
No data available
Plasmids
No data available