Gene

trpv6

ID

ZDB-GENE-040624-12

Name

transient receptor potential cation channel, subfamily V, member 6

Symbol

trpv6 Nomenclature History

Previous Names

ecac (1)
matt-und-schlapp (1)
mus (1)
zECaC (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Exhibits calcium channel activity. Involved in several processes, including calcium ion import; hypotonic salinity response; and response to calcium ion. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in hyperparathyroidism. Is expressed in several structures, including ball; digestive system; gill; integument; and pleuroperitoneal region. Orthologous to several human genes including TRPV6 (transient receptor potential cation channel subfamily V member 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

43 figures from 24 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trpv6 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Hyperparathyroidism, transient neonatal	618188

Associated With trpv6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005821	Ion transport domain
Family	IPR008344	Transient receptor potential cation channel subfamily V member 5/6
Family	IPR024862	Transient receptor potential cation channel subfamily V
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat