ZFIN is now using GRCz12tu for Genomic Data
Gene

pex5

ID
ZDB-GENE-040426-981
Name
peroxisomal biogenesis factor 5
Symbol
pex5 Nomenclature History
Previous Names
  • zgc:56318
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to be located in cytosol and peroxisomal matrix. Is expressed in liver. Used to study Zellweger syndrome. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Bhandari et al., 2023
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pex5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
peroxisome biogenesis disorder 2A Alliance Peroxisome biogenesis disorder 2A (Zellweger) 214110
peroxisome biogenesis disorder 2B Alliance Peroxisome biogenesis disorder 2B 202370
rhizomelic chondrodysplasia punctata type 5 Alliance Rhizomelic chondrodysplasia punctata, type 5 616716
Associated With pex5 Via Experimental Models
Human Disease Fish Conditions Citations
Zellweger syndrome pex5wk5/wk5 standard conditions Bhandari et al., 2023
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR024111 PEX5/PEX5L
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Repeat IPR019734 Tetratricopeptide repeat
Domain Details Per Protein
Protein Additional Resources Length PEX5/PEX5L Tetratricopeptide-like helical domain superfamily Tetratricopeptide repeat
UniProtKB:Q7ZUZ1 InterPro 600
UniProtKB:A0A8M3AHU4 InterPro 645
UniProtKB:A0A8M3B1G9 InterPro 416
UniProtKB:A0AB32T620 InterPro 641
UniProtKB:A0AC58HFT4 InterPro 637
UniProtKB:A0AC58HFT6 InterPro 600
UniProtKB:A0AC58HFT8 InterPro 678
UniProtKB:A0AC58HFT9 InterPro 637
UniProtKB:A0AC58HFU0 InterPro 678
UniProtKB:A0AC58HFU1 InterPro 641
UniProtKB:A0AC58HFV0 InterPro 600
UniProtKB:A0AC58HFW1 InterPro 678
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pex5-201 (1)
Ensembl
Ensembl 2,699 nt
ZFIN BLAST
mRNA pex5-202 (1)
Ensembl
Ensembl 2,344 nt
ZFIN BLAST
mRNA pex5-203 (1)
Ensembl
Ensembl 1,826 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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