ZFIN is now using GRCz12tu for Genomic Data
Gene
acad8
- ID
- ZDB-GENE-040426-828
- Name
- acyl-CoA dehydrogenase family, member 8
- Symbol
- acad8 Nomenclature History
- Previous Names
-
- zgc:55874
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable flavin adenine dinucleotide binding activity and short-chain 2-methyl fatty acyl-CoA dehydrogenase activity. Predicted to be involved in lipid metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Orthologous to human ACAD8 (acyl-CoA dehydrogenase family member 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55874 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Isobutyryl-CoA dehydrogenase deficiency | 611283 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR006089 | Acyl-CoA dehydrogenase, conserved site |
| Domain | IPR006091 | Acyl-CoA dehydrogenase/oxidase, middle domain |
| Domain | IPR009075 | Acyl-CoA dehydrogenase/oxidase, C-terminal |
| Domain | IPR013786 | Acyl-CoA dehydrogenase/oxidase, N-terminal |
| Family | IPR034178 | Isobutyryl-CoA dehydrogenase |
| Family | IPR052547 | Mitochondrial Isobutyryl-CoA Dehydrogenase |
| Homologous_superfamily | IPR009100 | Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily |
| Homologous_superfamily | IPR036250 | Acyl-CoA dehydrogenase-like, C-terminal |
| Homologous_superfamily | IPR037069 | Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily |
| Homologous_superfamily | IPR046373 | Acyl-CoA oxidase/dehydrogenase, middle domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Acyl-CoA dehydrogenase, conserved site | Acyl-CoA dehydrogenase-like, C-terminal | Acyl-CoA dehydrogenase/oxidase, C-terminal | Acyl-CoA dehydrogenase/oxidase, middle domain | Acyl-CoA dehydrogenase/oxidase, N-terminal | Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily | Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily | Acyl-CoA oxidase/dehydrogenase, middle domain superfamily | Isobutyryl-CoA dehydrogenase | Mitochondrial Isobutyryl-CoA Dehydrogenase |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZYY0 | InterPro | 418 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers