Gene
exo1
- ID
- ZDB-GENE-040426-2828
- Name
- exonuclease 1
- Symbol
- exo1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have 5'-flap endonuclease activity and single-stranded DNA 5'-3' exodeoxyribonuclease activity. Predicted to be involved in DNA recombination and mismatch repair. Predicted to localize to nucleus. Is expressed in proliferative region. Orthologous to human EXO1 (exonuclease 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7149750 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR008918 | Helix-hairpin-helix motif, class 2 |
| Conserved_site | IPR019974 | XPG conserved site |
| Domain | IPR006085 | XPG, N-terminal |
| Domain | IPR006086 | XPG-I domain |
| Domain | IPR037315 | Exonuclease-1, H3TH domain |
| Domain | IPR044752 | Exonuclease 1-like, PIN-like domain |
| Family | IPR006084 | XPG/Rad2 endonuclease |
| Homologous_superfamily | IPR029060 | PIN-like domain superfamily |
| Homologous_superfamily | IPR036279 | 5'-3' exonuclease, C-terminal domain superfamily |
| Repeat | IPR019734 | Tetratricopeptide repeat |
Domain Details Per Protein
| Protein | Length | 5'-3' exonuclease, C-terminal domain superfamily | Exonuclease-1, H3TH domain | Exonuclease 1-like, PIN-like domain | Helix-hairpin-helix motif, class 2 | PIN-like domain superfamily | Tetratricopeptide repeat | XPG conserved site | XPG-I domain | XPG, N-terminal | XPG/Rad2 endonuclease |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q803U7
|
806 |
Interactions and Pathways
No data available
Plasmids
No data available