Gene

uba3

ID
ZDB-GENE-040426-2825
Name
ubiquitin-like modifier activating enzyme 3
Symbol
uba3 Nomenclature History
Previous Names
  • ube1c (1)
  • wu:fb75e04
  • wu:fc37b11
  • zgc:55528
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have NEDD8 activating enzyme activity. Predicted to be involved in protein neddylation. Predicted to localize to cytoplasm and nucleus. Orthologous to human UBA3 (ubiquitin like modifier activating enzyme 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With uba3 Human Ortholog
No data available
Associated With uba3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR033127 Ubiquitin-activating enzyme E1, Cys active site
Domain IPR000594 THIF-type NAD/FAD binding fold
Domain IPR014929 E2 binding
Domain IPR030468 NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain
Family IPR045886 ThiF/MoeB/HesA family
Homologous_superfamily IPR023318 Ubiquitin activating enzyme, alpha domain superfamily
Homologous_superfamily IPR035985 Ubiquitin-activating enzyme
Domain Details Per Protein
Protein Length E2 binding NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain ThiF/MoeB/HesA family THIF-type NAD/FAD binding fold Ubiquitin-activating enzyme Ubiquitin activating enzyme, alpha domain superfamily Ubiquitin-activating enzyme E1, Cys active site
UniProtKB:Q7ZVX6 462
UniProtKB:A0A8M2B283 449
UniProtKB:B2GSP4 462
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA uba3-201 (1) Ensembl 1,805 nt
mRNA uba3-202 (1) Ensembl 699 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations