Gene
lipf
- ID
- ZDB-GENE-040426-2737
- Name
- lipase, gastric
- Symbol
- lipf Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable hydrolase activity, acting on ester bonds. Acts upstream of or within cholesterol homeostasis and response to hypoxia. Is expressed in gill and liver. Human ortholog(s) of this gene implicated in Wolman disease and cholesterol ester storage disease. Orthologous to several human genes including LIPA (lipase A, lysosomal acid type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Han et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Alpha/beta hydrolase fold-1 | Lipase, eukaryotic |
|---|---|---|---|---|
|
UniProtKB:Q7ZTR9
|
396 |
Interactions and Pathways
No data available
Plasmids
No data available