Gene

klhl21

ID
ZDB-GENE-040426-2627
Name
kelch-like family member 21
Symbol
klhl21 Nomenclature History
Previous Names
  • zgc:76933
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including chromosome passenger complex localization to spindle midzone; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to act upstream of or within cell division. Predicted to be located in polar microtubule. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human KLHL21 (kelch like family member 21).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
No data available
Human Disease
Associated With klhl21 Human Ortholog
No data available
Associated With klhl21 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR011705 BTB/Kelch-associated
Domain IPR030577 Kelch-like protein 21, BTB/POZ domain
Domain IPR047069 Kelch-like protein 21, BACK domain
Family IPR017096 BTB-kelch protein
1 - 5 of 8 Show all
Domain Details Per Protein
Protein Length BTB/Kelch-associated BTB-kelch protein BTB/POZ domain Kelch-like protein 21, BACK domain Kelch-like protein 21, BTB/POZ domain Kelch repeat type 1 Kelch-type beta propeller SKP1/BTB/POZ domain superfamily
UniProtKB:Q6NYM1 613
UniProtKB:A0A8M9P526 613
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 23
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA klhl21-201 (1) Ensembl 523 nt
mRNA klhl21-202 (1) Ensembl 3,896 nt
mRNA klhl21-203 (1) Ensembl 3,902 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-7I1
EncodescDNAMGC:76933ZFIN Curated Data
EncodescDNAMGC:175048ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanKLHL211
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
MouseKlhl214
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 3 of 3
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