Gene

spred1

ID
ZDB-GENE-040426-2338
Name
sprouty related EVH1 domain containing 1
Symbol
spred1 Nomenclature History
Previous Names
  • fb14c08
  • fj51c03
  • wu:fb14c08 (1)
  • wu:fj51c03 (1)
  • zgc:85707 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have protein kinase binding activity. Involved in blood vessel morphogenesis; lymph vessel development; and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to localize to membrane. Orthologous to human SPRED1 (sprouty related EVH1 domain containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spred1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Legius syndrome Alliance Legius syndrome 611431
Associated With spred1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000697 WH1/EVH1 domain
Domain IPR023337 c-Kit-binding domain
Domain IPR041937 SPRE, EVH1 domain
Family IPR007875 Sprouty
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length c-Kit-binding domain PH-like domain superfamily SPRE, EVH1 domain Sprouty WH1/EVH1 domain
UniProtKB:Q6NV01 391
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations