Gene
hnrnpc
- ID
- ZDB-GENE-040426-2043
- Name
- heterogeneous nuclear ribonucleoprotein C
- Symbol
- hnrnpc Nomenclature History
- Previous Names
-
- fb57h12
- fi16b11
- wu:fb57h12 (1)
- wu:fi16b11
- zgc:55701
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Enables mRNA 3'-UTR binding activity. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to several human genes including HNRNPC (heterogeneous nuclear ribonucleoprotein C); HNRNPCL3 (heterogeneous nuclear ribonucleoprotein C like 3); and HNRNPCL4 (heterogeneous nuclear ribonucleoprotein C like 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55701 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 74 | Alliance | Intellectual developmental disorder, autosomal dominant 74 | 620688 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Family | IPR017347 | Heterogeneous nuclear ribonucleoprotein C |
| Family | IPR051186 | RRM HNRPC family, RALY subfamily |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Heterogeneous nuclear ribonucleoprotein C | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | RRM HNRPC family, RALY subfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q728
|
393 | |||||
|
UniProtKB:Q803J4
|
313 | |||||
|
UniProtKB:A0A8M6Z8V1
|
312 | |||||
|
UniProtKB:A0A8M9PUR6
|
392 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hnrnpc-201
(1)
|
Ensembl | 1,726 nt |
Interactions and Pathways
No data available
Plasmids
No data available