Gene
ripk4
- ID
- ZDB-GENE-040426-2042
- Name
- receptor-interacting serine-threonine kinase 4
- Symbol
- ripk4 Nomenclature History
- Previous Names
-
- wu:fj80b10
- zgc:55705
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and protein kinase activity. Predicted to be involved in protein phosphorylation. Is expressed in several structures, including EVL; digestive system; ectoderm; epidermis; and peripheral olfactory organ. Orthologous to human RIPK4 (receptor interacting serine/threonine kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55705 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| popliteal pterygium syndrome | Alliance | Popliteal pterygium syndrome, Bartsocas-Papas type 1 | 263650 |
| CHAND syndrome | 214350 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q8JHU3
|
820 |
Interactions and Pathways
No data available
Plasmids
No data available