Gene
med15
- ID
- ZDB-GENE-040426-2032
- Name
- mediator complex subunit 15
- Symbol
- med15 Nomenclature History
- Previous Names
-
- fi85b10
- pcqap (1)
- wu:fd19g01
- wu:fi19d01
- wu:fi85b10
- zgc:55839
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable transcription coregulator activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleoplasm. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MED15 (mediator complex subunit 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55839 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lin et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR019087 | Mediator of RNA polymerase II transcription subunit 15, N-terminal |
| Domain | IPR048385 | ARC105/Med15 mediator subunit, central domain |
| Domain | IPR048386 | ARC105/Med15 mediator subunit, C-terminal domain |
| Homologous_superfamily | IPR036529 | Coactivator CBP, KIX domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | ARC105/Med15 mediator subunit, central domain | ARC105/Med15 mediator subunit, C-terminal domain | Coactivator CBP, KIX domain superfamily | Mediator of RNA polymerase II transcription subunit 15, N-terminal |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PTS3 | InterPro | 766 | ||||
| UniProtKB:A0A8M9PI73 | InterPro | 801 | ||||
| UniProtKB:Q7ZVN7 | InterPro | 809 | ||||
| UniProtKB:F1QFA9 | InterPro | 802 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available