ZFIN is now using GRCz12tu for Genomic Data
Gene
poc1a
- ID
- ZDB-GENE-040426-1993
- Name
- POC1 centriolar protein A
- Symbol
- poc1a Nomenclature History
- Previous Names
-
- wdr51a
- wu:fl82d01
- zgc:56055
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in cilium assembly. Predicted to be active in centriole and ciliary basal body. Human ortholog(s) of this gene implicated in hypotrichosis. Orthologous to human POC1A (POC1 centriolar protein A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56055 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis | 614813 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Family | IPR050505 | WD repeat-containing protein 55/POC1 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | PAC1/LIS1-like, WD-40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | PAC1/LIS1-like, WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat-containing protein 55/POC1 |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZVF0 | InterPro | 416 | ||||||
| UniProtKB:A0AC58GPV7 | InterPro | 416 | ||||||
| UniProtKB:A0AC58GPW5 | InterPro | 416 | ||||||
| UniProtKB:A0AC58GPW9 | InterPro | 372 | ||||||
| UniProtKB:A0AC58GPY0 | InterPro | 348 | ||||||
| UniProtKB:A0AC58GPY1 | InterPro | 375 | ||||||
| UniProtKB:A0AC58GPY7 | InterPro | 440 | ||||||
| UniProtKB:A0AC58GQ01 | InterPro | 348 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers