Gene
necap1
- ID
- ZDB-GENE-040426-1682
- Name
- NECAP endocytosis associated 1
- Symbol
- necap1 Nomenclature History
- Previous Names
-
- zgc:73124 (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to be involved in vesicle-mediated transport. Predicted to act upstream of or within endocytosis. Predicted to be located in membrane. Predicted to be part of clathrin vesicle coat. Is expressed in central nervous system and epiphysis. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 21. Orthologous to human NECAP1 (NECAP endocytosis associated 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73124 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 21 | Alliance | Developmental and epileptic encephalopathy 21 | 615833 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NECAP, PHear domain | PH-like domain superfamily |
|---|---|---|---|
|
UniProtKB:Q6PC36
|
261 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
necap1-201
(1)
|
Ensembl | 1,562 nt | ||
| mRNA |
necap1-202
(1)
|
Ensembl | 745 nt |
Interactions and Pathways
No data available
Plasmids
No data available