Gene

sars2

ID

ZDB-GENE-040426-1616

Name

seryl-tRNA synthetase 2, mitochondrial

Symbol

sars2 Nomenclature History

Previous Names

zgc:66345 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have serine-tRNA ligase activity and tRNA binding activity. Predicted to be involved in mitochondrial seryl-tRNA aminoacylation. Predicted to localize to mitochondrion. Orthologous to human SARS2 (seryl-tRNA synthetase 2, mitochondrial).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:66345 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sars2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Hyperuricemia, pulmonary hypertension, renal failure, and alkalosis	613845

Associated With sars2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002314	Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
Domain	IPR006195	Aminoacyl-tRNA synthetase, class II
Domain	IPR033729	Serine-tRNA ligase catalytic core domain
Family	IPR002317	Serine-tRNA ligase, type1
Homologous_superfamily	IPR010978	Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm
Homologous_superfamily	IPR042103	Serine-tRNA synthetase, type1, N-terminal domain superfamily
Homologous_superfamily	IPR045864	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)